منابع مشابه
Bendectin and birth defects. II: Ecological analyses.
BACKGROUND Bendectin was the primary pharmaceutical treatment of nausea and vomiting of pregnancy (NVP) in the United States until the early 1980s. Its manufacture was then discontinued after public allegations that it was causing birth defects. Subsequently, meta-analyses of the many epidemiological cohort and case/control studies used to examine that hypothesis have demonstrated the absence o...
متن کاملBendectin and birth defects: hopefully, the final chapter.
The study published in this issue of Birth Defects Research Part A, “Bendectin and Birth Defects: Ecological Analysis,” by Kutcher et al. (2002) deals with two aspects pertaining to the effects of Bendectin. It is an excellent research article. The first area investigated was related to the question as to whether Bendectin was a human teratogen based on ecological analysis. The second area inve...
متن کاملACUTE EXTRAPYRAMIDAL SYMPTOMS FOLLOWING ABRUPT DISCONTINUATION OF PROPRANOLOL
A case of acute extrapyramidal manifestations consisting of dystonia and akathisia following abrupt discontinuation of propranolol is reported. She responded well to oral propranolol and intramuscular diazepam. Extrapyramidal symptoms have commonly been associated with acute or chronic administration of neuroleptic drugs. There have been reports of a substantial number of cases with simila...
متن کاملDiscontinuation of pediatric trials.
It is said that a research study is completed when its results are submitted for consideration to the scientific community, which will ultimately assess, accept, and eventually adopt those results. In order for our peers to determine the validity of a scientific study, they need to get all the information about the study to adequately review its methodological rigor and the significance of its ...
متن کاملDiscontinuation Decision in Assisted Reproductive Techniques
Background In vitro fertilization (IVF) and intra cytoplasmic sperm injection (ICSI) are recognized as established and increasingly successful forms of treatment for infertility, yet significant numbers of couples discontinue treatment without achieving a live birth. This study aims to identify major factors that influence the decision to discontinue IVF/ICSI treatments. MaterialsAndMethods We ...
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ژورنال
عنوان ژورنال: American Journal of Public Health
سال: 1988
ISSN: 0090-0036,1541-0048
DOI: 10.2105/ajph.78.3.322-a